Metabonomic相关论文
Study on the Intervention Effects of Pinggan Prescription (平肝方) on Spontaneously Hypertensive Rats B
Objective: To investigate the effects of Pinggan Prescription (平肝方, PGP) on hypertension by the associated methods of......
The metabolic profile differentiation between ageing and normal female rats based on 1H-NMR metabono
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Methodological validations of metabonomic analysis are far from being perfect.This research tends to validate the possib......
Methological considerations of an HPLC-QTRAP based method for metabonomic analysis: application to h
Objective: To investigate methological considerations of an HPLC-QTRAP based method for metabonomic analysis and applied......
Therapeutic effects of Selaginella tamariscina on the model of acute gout with hyperuricemia in rats
Gout is a common inflammatory arthritis and is caused by sodium urate deposition in and around the joints and resulted f......
Metabonomic analysis of plasma biochemical changes in pyrexia rats after treatment with Gegenqinlian
A metabonomic approach involving an ultrahigh-performance liquid chromatography combined with Fourier transform ion cycl......
Establishing 1H nuclear magnetic resonance based metabonomics fingerprinting profile for spinal cord
Background Spinal cord injury (SCI) is a complex trauma that consists of multiple pathological mechanisms involving cyto......
Therapeutic Effects of Selaginella tamariscina on the Model of Acute Gout with Hyperuricemia in Rats
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的：运用代谢组学方法阐明经典激活型（M 1型）、选择活化型（M 2型）和静息态小胶质细胞的代谢差异。方法将体外培养小鼠小胶质细胞系（BV2）......
Establishing 1H nuclear magnetic resonance based metabonomics fingerprinting profile for spinal cord
Background Spinal cord injury (SCI) is a complex trauma that consists of multiple pathological mechanisms involving cyto......
Metabonomic analysis of plasma biochemical changes in pyrexia rats after treatment with Gegenqinlian
A metabonomic approach involving an ultrahigh-performance liquid chromatography combined with Fourier transform ion cycl......
目的研究2型糖尿患者与健康者血清和粪便的代谢组学差异,分析差异代谢物与2型糖尿病之间的相关性。方法选择2018年1月至2019年3月......
应用基于核磁共振的代谢组学方法研究Ⅱ型糖尿病模型db/db小鼠已发展到糖尿病肾病时肾脏代谢表型的变化.结合偏最小二乘法-判别分......
目的研究Z24染毒大鼠血浆的代谢表型改变及其与组织病理和血液生化指标的相关性,探讨代谢组学在药物毒性早期筛选中的应用.方法 Wi......
采用基于LC/Q-TOF MS的代谢组学方法,对不同致病性青枯雷尔氏菌的胞外代谢物进行了分析,获得了具有显著性差异的代谢标志物,并采用......
目的寻找中青年高血压病痰湿壅盛证患者的尿液生物标记群,探索其证候本质。方法运用1H NMR结合PLS-DA的方法对中青年高血压病三种......
背景与目的：运用代谢组学技术检测纳米铜染毒大鼠的血清代谢成分变化，结合常规血液生化及组织病理学检查，探讨纳米铜短期暴露的损害特......
[目的]运用代谢组学方法,研究正天丸治疗偏头痛的机制。[方法]给药和造模后取大鼠血浆,通过超高效液相色谱结合高分辨率飞行时间质......
数据归一化是预处理中的重要组成部分,本文采用正常大鼠与I型糖尿病模型大鼠的尿液核磁共振谱图作为测试数据,研究了线归一、面归......
建立了一种基于气相色谱．质谱（GC—MS）技术的代谢组学分析方法。以CCl4致小鼠肝损伤模型为研究对象，检测了染毒小鼠肝组织和血浆中内源......
代谢组学是研究机体代谢网络和代谢产物与机体所处环境之间联系的重要方法,与中医药的基本理论和诊疗思维有异曲同工之处,为研究复......
